New Chiral α‐Benzyloxyacryliron( II ) Complex for Asymmetric Synthesis of α, α‐Dialkyl‐α‐hydroxycarbonyl Compounds | Zendy

Stolz Felix | Zendy; Strazewski Peter | Zendy; Tamm Christoph | Zendy; Neuburger Markus | Zendy; Zehnder Margareta | Zendy

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New Chiral α‐Benzyloxyacryliron( II ) Complex for Asymmetric Synthesis of α, α‐Dialkyl‐α‐hydroxycarbonyl Compounds

Author(s) -

Stolz Felix,

Strazewski Peter,

Tamm Christoph,

Neuburger Markus,

Zehnder Margareta

Publication year - 1992

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.199201931

Subject(s) - hydrogenolysis , enantiomer , chemistry , chirality (physics) , stereospecificity , stereochemistry , alkylation , cleavage (geology) , catalysis , organic chemistry , chiral symmetry , materials science , physics , quantum mechanics , fracture (geology) , nambu–jona lasinio model , composite material , quark

From simple achiral starting materials the chiral organoiron( II ) complex 1 can be prepared as either the R or S enantiomer. A Michael addition and subsequent stereospecific alkylation followed by oxidative cleavage of the Fe complex fragment and hydrogenolysis of the O ‐benzyl function yields the α,α‐dialkyl‐α‐hydroxycarbonyl compounds with the desired chirality.

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