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Bicyclocalix[4]arenes
Author(s) -
Berger Bettina,
Böhmer Volker,
Paulus Erich,
Rodriguez Amado,
Vogt Walter
Publication year - 1992
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199200961
Subject(s) - bridging (networking) , ketone , phenol , unit (ring theory) , aldol condensation , methyl ketone , condensation , chemistry , stereochemistry , organic chemistry , physics , mathematics , computer science , catalysis , computer network , thermodynamics , mathematics education
The construction of a macrobicycle from three calix[4]arene units as in 2 can be achieved by a double aldol condensation of 1 , a nitromalonaldehyde with a bridging ketone unit. In the crystal the newly formed nitrophenol unit is virtually parallel to one of the nonbridged phenol units; in solution it swings in the cavity of the calix[4]arene A‐B‐C‐D like the clapper of a bell. R = cyclo ‐C 6 H 11 .