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First Example of a Chlorophin from an Unexpected Oxidative Ring‐Opening of an (Octadehydrocorrinato)nickel( II ) Salt
Author(s) -
Chang Chi K.,
Wu Weishih,
Chern ShuennShing,
Peng ShieMing
Publication year - 1992
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199200701
Subject(s) - ring (chemistry) , chemistry , nickel , salt (chemistry) , pyrrole , furan , combinatorial chemistry , inorganic chemistry , chloride , photochemistry , medicinal chemistry , polymer chemistry , organic chemistry
A tetraazamacrocycle from three pyrrole units and a condensed furan ring —“furochloro‐phin”—surrounds the Ni II ion in 1 . This 18π electron system with a basic chlorin structure is formed surprisingly easily from the thermolysis of (octadehydrocorrinato)nickel( II ) chloride. This synthesis will probably not only provide new impetus for corrinoid chemistry; but the absorption characteristics of the metal complex and the free base make these interesting compounds for applications in photodynamic cancer therapy.