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Metal‐Assisted Organization rather than Preorganization for the Design of Macrocyclic Hosts
Author(s) -
Kobuke Yoshiaki,
Sumida Yasutaka,
Hayashi Minoru,
Ogoshi Hisanobu
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199114961
Subject(s) - alkali metal , boric acid , flexibility (engineering) , chemistry , metal , bicyclic molecule , combinatorial chemistry , stereochemistry , inorganic chemistry , nanotechnology , materials science , organic chemistry , mathematics , statistics
Boric acid initiates the formation of coronand 1 from 2 , providing the framework necessary for the strong complexation of alkali metal ions. This approach to the synthesis of the macrocyclic host allows a greater flexibility than the standard preorganization method. A bicyclic coronand is also obtained by this strategy. M = K, Na.