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Fischer Carbene Complexes Facilitate the Intramolecular Pauson‐Khand Reaction
Author(s) -
Camps Francisco,
Moretó Josep M.,
Ricart Susagna,
Viñas Josep M.
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199114701
Subject(s) - pauson–khand reaction , carbene , cyclopentenone , intramolecular force , bicyclic molecule , chemistry , alkyne , olefin fiber , transition metal carbene complex , medicinal chemistry , catalysis , organic chemistry
One of the most efficient organometallic reactions in organic synthesis, the Pauson–Khand reaction is accelerated by the incorporation of the olefin and alkyne reaction partners in a Fischer carbene complex. The bicyclic cyclopentenone derivatives 2 , obtained from 1 after a few hours reaction at roomtemperature, are highly functionalized and lend themselves to further reactions.