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Metal‐Ion Dependent Regioselectivity in Cyclometalation Reactions
Author(s) -
Constable Edwin C.,
Henney Roland P. G.,
Raithby Paul R.,
Sousa Lynn R.
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199113631
Subject(s) - metalation , regioselectivity , chemistry , ring (chemistry) , ligand (biochemistry) , pyridine , chelation , metal , stereochemistry , coordination sphere , medicinal chemistry , inorganic chemistry , catalysis , organic chemistry , receptor , biochemistry
A dimeric gold( III ) complex , the 18‐membered ring system 1 , is formed on treatment of Na[AuCl 4 ] with the potentially chelating lig‐and 6‐(2‐thienyl)‐2,2′‐bipyridine (HL). Metalation of the thienyl unit occurs in the 5‐position, and the coordination sphere of gold also includes two trans Cl ligands and an N atom from the terminal pyridine of the second HL ligand. In contrast, Pd II and Pt II form cyclometalated complexes of the type [MLCl].