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Methylating Reductive Dimerization of Aromatic Carbonyl Compounds, a Novel Organometallic Reaction
Author(s) -
Kauffmann Thomas,
Jordan Jan,
Voss KarlUwe
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199111381
Subject(s) - methyllithium , chemistry , aldehyde , organic chemistry , methylation , coupling reaction , organometallic chemistry , medicinal chemistry , catalysis , biochemistry , gene
A novel reaction related to the McMurry reaction , the coupling of aromatic aldehydes and ketones according to Equation (a), is found to take place after methylation of the W V complexes 1 with methyllithium. The yields of 2 are 76–90% (five examples); the reaction does not take place with aliphatic aldehydes and ketones.
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