Premium
Novel Polymeric Materials from Monodisperse Copolypeptides by Biotechnological Methods
Author(s) -
Ritter Helmut
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199106771
Subject(s) - dispersity , homogeneous , casual , sequence (biology) , nanotechnology , polymer science , materials science , chemistry , chemical engineering , organic chemistry , mathematics , engineering , biochemistry , composite material , combinatorics
“The ox can do it better.” This casual, yet time‐tested remark by Emil Fischer with reference to the synthesis of peptides has stimulated almost a generation of preparative chemists to take up the challenge. And, “the ox” has recently met with increasing competition through the introduction of modern biotechnological methods. Though these methods have largely been limited to the successful synthesis of active substances in the pharmaceutical and agricultural sectors in recent years, a breakthrough now seems to have been made by D. A. Tirrell et al. in the preparation of new materials. A cyclopeptide with exactly 14 repeat units of an undecapeptide sequence has been prepared which has a glass temperature of 182°C, decomposes above 250°C, and from which homogeneous films can be cast.