Isoselective Relationship for the Stereoselectivity of the Transfer of Hydrogen Atoms to Cyclic Alkyl Radicals | Zendy

Giese Bernd | Zendy; Farshchi Hassan | Zendy; Hartmanns Jörg | Zendy; Metzger Jürgen O. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Isoselective Relationship for the Stereoselectivity of the Transfer of Hydrogen Atoms to Cyclic Alkyl Radicals

Author(s) -

Giese Bernd,

Farshchi Hassan,

Hartmanns Jörg,

Metzger Jürgen O.

Publication year - 1991

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.199106001

Subject(s) - radical , chemistry , stereoselectivity , selectivity , alkyl , medicinal chemistry , stereochemistry , catalysis , organic chemistry

An isoselectivity relationship despite variation of two reaction partners was found for H transfer to the radicals 1 . The isoselectivity point is characterized by T iso = 750 K and ( Z ) ‐2 /( E ) ‐2 = 0.72 ± 0.07 (X = O, PhN; R′ = Me, n ‐C 6 H 13 , PhCH 2 , c ‐C 6 H 11 , PhCH(Me); RH = Bu 3 SnH, PhMe, PhEt, c ‐C 6 H 12 ). Thus, control of the selectivity of such product‐forming reaction steps is possible by, for example, variation of the β substituents of the H donor and the reaction temperature.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research