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Highly Stable Liposomes Derived from Perfluoroalkylated Glycerophosphocholines
Author(s) -
Santaella Catherine,
Vierling Pierre,
Riess Jean G.
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199105671
Subject(s) - liposome , membrane , vesicle , alkyl , lecithin , chemistry , organic chemistry , chromatography , chemical engineering , biochemistry , engineering
Vesicles prepared from modified lecithin lipids such as 1 are characterized by an increased, monthlong stability. The fluorination of the ends of the alkyl chains also makes these compounds suitable as excellent emulgators of fluorinated hydrocarbons. Owing to their low toxicity, they are of interest for the preparation of artificial membranes and as carriers of pharmaceuticals.
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