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Catalytic Enantioselective Epoxidations of Simple Olefins
Author(s) -
Bolm Carsten
Publication year - 1991
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199104031
Subject(s) - enantioselective synthesis , catalysis , alkyl , chemistry , organic chemistry , aryl
Enantioselective catalytic oxidations of nonfunctionalized alkenes (Equation (a), X = H, alkyl, aryl) remained a challenge long after Sharpless and co‐workers developed the enantioselective epoxidation of allyl alcohols (Equation (a), X = OH) ten years ago. Designer catalysts based on porphyrins recently brought new progress, while poly‐ L ‐leucine proved attractive as catalyst for the epoxidation of diverse chalcones with H 2 O 2 /NaOH in up to 92% ee.
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