Hydrogenobyrinic Acid: Isolation, Biosynthesis, and Function | Zendy

Blanche Francis | Zendy; Thibaut Denis | Zendy; Frechet Denise | Zendy; Vuilhorgne Marc | Zendy; Crouzet Joel | Zendy; Cameron Béatrice | Zendy; Hlineny Kersten | Zendy; TraubEberhard Ute | Zendy; Zboron Maureen | Zendy; Müller Gerhard | Zendy

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Hydrogenobyrinic Acid: Isolation, Biosynthesis, and Function

Author(s) -

Blanche Francis,

Thibaut Denis,

Frechet Denise,

Vuilhorgne Marc,

Crouzet Joel,

Cameron Béatrice,

Hlineny Kersten,

TraubEberhard Ute,

Zboron Maureen,

Müller Gerhard

Publication year - 1990

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.199008841

Subject(s) - biosynthesis , vitamin b12 , function (biology) , biochemistry , isolation (microbiology) , chemistry , biology , bioinformatics , enzyme , genetics

The cobalt‐free analogue of the vitamin‐ B 12 parent substance cobyrinic acid 2 , the hydrogenobyrinic acid 1 , has been made available by a biosynthetic method. This opens up new possibilities for studies on the biosynthesis of 1 and 2 as well as on their chemistry. The first investigations on the biosynthesis and function of 1 are reported; and a complete assignment of the 1 H‐ and 13 C‐NMR signals of 1 is given.

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