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Zn II Fe III and Fe II Fe III Complexes Containing a Novel (μ‐Phenoxo)bis(μ‐diphenylphosphato)‐dimetal( II,III ) Core as Model Complexes for Active Sites of Purple Phosphatases
Author(s) -
Schepers Klaus,
Bremer Bernd,
Krebs Bernt,
Henkel Gerald,
Althaus Erika,
Mosel Bernd,
MüllerWarmuth Werner
Publication year - 1990
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199005311
Subject(s) - chemistry , crystallography , bimetallic strip , phosphate , ion , stereochemistry , nuclear chemistry , radiochemistry , inorganic chemistry , catalysis , biochemistry , organic chemistry
What is the mechanism of action of the purple phosphatases? It is known that these important enzymes contain bimetallic centers with mixed valences (e.g., Zn II Fe III or Fe II Fe III ) as well as coordinated phosphate. The title compounds are model complexes with two phosphate and one heptadentate (6 N, 1 O) bridging ligands. The model complexes and the enzyme compare quite favorably in several respects. • (left) = Fe; • (right) = Zn;