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A Facile Synthesis of β‐Selenolactams
Author(s) -
Ishihara Hideharu,
Yoshimi Michinari,
Kato Shinzi
Publication year - 1990
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199005301
Subject(s) - yield (engineering) , amine gas treating , chemistry , medicinal chemistry , organic chemistry , materials science , metallurgy
The cis β‐selenolactams 1 have been obtained in 70–89% yield by reaction (a). The only exception encountered was the amine in which R 1 = 4‐CH 3 C 6 H 4 , R 2 = i ‐C 3 H 7 a compound that led to a mixture of cis (59%) and trans (10%) isomers. R 1 = C 6 H 5 , 4‐CH 3 C 6 H 4 ; R 2 = C 6 H 5 , i ‐C 3 H 7 , 4‐CH 3 C 6 H 4 ,C 6 H 5 CH 2 , 4‐ClC 6 H 4 .