Premium
Unraveling Overlapping Multiplets in Two‐Dimensional NMR Correlation Spectra by Selective Inversion of Coupling Partners
Author(s) -
Emsley Lyndon,
Huber Peter,
Bodenhausen Geoffrey
Publication year - 1990
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199005171
Subject(s) - multiplet , coupling constant , spectral line , coupling (piping) , physics , spectrum (functional analysis) , nuclear magnetic resonance , simple (philosophy) , chemistry , molecular physics , materials science , quantum mechanics , philosophy , epistemology , metallurgy
Clean and simple two‐dimensional multiplet pallerns instead of overlapping multiplets can be generated in an NMR experiment by employing selective pulses that single out small segments of a complete spectrum. The pattern of the selected multiplet is in this case manipulated by altering the apparent signs of the coupling constants. The technique is suitable not only for separating overlapping signals, but also for testing hypotheses associated with particular coupling networks.