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What Are the Structures of Fenestin A and Fenestin B?
Author(s) -
Schmidt Ulrich,
Lieberknecht Albrecht,
Kazmaier Uli,
Haslinger Ernst
Publication year - 1990
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199005141
Subject(s) - field (mathematics) , image (mathematics) , dimer , stereochemistry , chemistry , computer science , mathematics , artificial intelligence , pure mathematics , organic chemistry
1 H NMR signals at unusually high field (δ = 3.9–4.1 rather than 4.0–4.6 as in known cyclopeptides) render the proposed structures 1 and 2 unlikely for fenestin A and fenestin B, two cyclopeptides isolated from Pacific sponges. Synthesis and analysis of the postulated compound 2 as well as the dimer of 1 have made it possible to show that the suggested structure for fenestin B is wrong, while that for fenestin A must at least be regarded as questionable.