Solid‐Phase Synthesis of Glycopeptide Amides under Mild Conditions: Morphiceptin Analogues | Zendy

Bardají Eduard | Zendy; Torres Josep L. | Zendy; Clapés Pere | Zendy; Albericio Fernando | Zendy; Barany George | Zendy; Valencia Gregorio | Zendy

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Solid‐Phase Synthesis of Glycopeptide Amides under Mild Conditions: Morphiceptin Analogues

Author(s) -

Bardají Eduard,

Torres Josep L.,

Clapés Pere,

Albericio Fernando,

Barany George,

Valencia Gregorio

Publication year - 1990

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.199002911

Subject(s) - glycopeptide , glycosidic bond , glycoprotein , chemistry , glycosyl , solid phase synthesis , glycan , phase (matter) , stereochemistry , combinatorial chemistry , biochemistry , peptide , organic chemistry , enzyme , antibiotics

Membrane glycoproteins belong to the most important compounds in living nature. The glycoprotein amides (morphiceptin analogous) have now become readily accessible by a solid‐phase method (glycosyl is galacto‐ or glucopyranosyl). Upon detachment from the carrier, the sensitive glycosidic bond remains intact.

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