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The Pagodane Route to Dodecahedranes: An Efficient Variant—New Substitution Patterns
Author(s) -
Pinkos Rolf,
Melder JohannPeter,
Prinzbach Horst
Publication year - 1990
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199000921
Subject(s) - substitution (logic) , sn2 reaction , computer science , chemistry , computational biology , stereochemistry , biology , programming language
The pagodane → dodecahedrane concept is extended significantly by the S N 2 synthetic variant, both from the preparative as well as the methodological standpoint. Starting from the pagodane‐bislactone 1 , dodecahedranes and homologous dodecahedranes with specific substitution patterns, e.g. 3 (R CO 2 CH 3 ), are accessible via the anti,anti,syn,syn‐dibromide esters 2 .
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