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Water‐Soluble Porphyrin Diglycosides with Photosensitizing Properties
Author(s) -
Fülling Gerd,
Schröder Doris,
Franck Burchard
Publication year - 1989
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198915191
Subject(s) - porphyrin , chemistry , water soluble , rose bengal , singlet oxygen , biophysics , combinatorial chemistry , biochemistry , oxygen , organic chemistry , biology
In the presence of oxygen, tumors and viruses can be destroyed by photosensitizing porphyrins. Indispensable for clinical applications is, inter alia, a good solubility in water. It has now been possible to prepare two porphyrin diglycosides which are water‐soluble and stable as well as equally strongly photosensitizing as Rose Bengal. With these properties they ideally fulfill the demands of a wide spectrum of photomedicinal applications.