Premium
The First Tricyclic Diaziridines—a Simple Synthetic Route
Author(s) -
Denisenko Sergej N.,
Pasch Eva,
Kaupp Gerd
Publication year - 1989
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198913811
Subject(s) - tricyclic , bicyclic molecule , simple (philosophy) , chemistry , protonation , computational chemistry , stability (learning theory) , stereochemistry , combinatorial chemistry , organic chemistry , computer science , ion , philosophy , epistemology , machine learning
The tricyclic diaziridines 1( n = 1, 2) are accessible in only two steps from simple lactams. In view of the abnormal calculated (AM1) bond angle at the quaternary carbon, their stability is remarkable : however, they can be easily transformed into bicyclic protonated azomethine imines.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom