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The First Tricyclic Diaziridines—a Simple Synthetic Route
Author(s) -
Denisenko Sergej N.,
Pasch Eva,
Kaupp Gerd
Publication year - 1989
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198913811
Subject(s) - tricyclic , bicyclic molecule , simple (philosophy) , chemistry , protonation , computational chemistry , stability (learning theory) , stereochemistry , combinatorial chemistry , organic chemistry , computer science , ion , philosophy , epistemology , machine learning
The tricyclic diaziridines 1( n = 1, 2) are accessible in only two steps from simple lactams. In view of the abnormal calculated (AM1) bond angle at the quaternary carbon, their stability is remarkable : however, they can be easily transformed into bicyclic protonated azomethine imines.