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The Enantiomers of the Azole Fungicide HWG‐1608—Asymmetric Synthesis of a 2‐Hydroxyethyl Azole Fungicide
Author(s) -
Kaulen Johannes
Publication year - 1989
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198904621
Subject(s) - fungicide , azole , enantiomer , chemistry , enantioselective synthesis , organic chemistry , combinatorial chemistry , biology , antifungal , botany , microbiology and biotechnology , catalysis
Only a few good procedures are available for the enantioselective synthesis of chiral tertiary alcohols. Both enantiomers of the highly effective fungicide 1 have now been prepared by the oxathiane method and are available in gram amounts for biological investigations.