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Gas Chromatographic Determination of the Enantiomeric Composition of Epoxy Alcohols
Author(s) -
König Wilfried A.,
Lutz Sabine,
Wenz Gerhard,
Görgen Günther,
Neumann Christoph,
Gäbler Andreas,
Boland Wilhelm
Publication year - 1989
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198901781
Subject(s) - epoxy , enantiomer , chemistry , chromatography , capillary gas chromatography , gas chromatography , composition (language) , organic chemistry , linguistics , philosophy
Enantiomeric excesses greater than 98% can now be determined exactly in the synthesis of chiral epoxy alcohols. Capillary chromatography on peralkylated cyclodextrins allows the trifluoroacetyl derivatives of epoxy alcohols such as ( E )‐2,3‐epoxy‐4‐octynol (picture on the right) and 2,3‐epoxypropanol to be separated into their enantiomers within a few minutes.