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Host‐Guest Bonding of Oxoanions to Guanidinium Anchor Groups
Author(s) -
Müller Gerhard,
Riede Jürgen,
Schmidtchen Franz Peter
Publication year - 1988
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198815161
Subject(s) - carboxylate , chemistry , titration , phosphate , host (biology) , stereochemistry , crystallography , inorganic chemistry , organic chemistry , ecology , biology
Adaptation of the recognition principle of many biogenic receptors , which make use of the interaction between the guanidinium function of arginyl side chains with carboxylate and phosphate groups of substrates, was used to design and synthesize new host compounds. The bicyclic guanidinium compounds ( 1 , shown schematically) bind p ‐nitrobenzoate (NMR‐titration) and acetate (X‐ray structural analysis).