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Trimethylplatinum‐Theophylline Hexamer: A Novel Pt 6 Heterocycle Containing Both PtN and PtO Bonds
Author(s) -
Lorberth Jörg,
Massa Werner,
E.Essawi Mohy,
Labib Lilian
Publication year - 1988
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198811601
Subject(s) - theophylline , random hexamer , denticity , ligand (biochemistry) , chemistry , octahedron , crystallography , stereochemistry , crystal structure , receptor , medicine , biochemistry , endocrinology
A cyclic hexamer of trimethylplatinum units and theophylline anions is a model substance for R‐DNA complexes. The Pt atoms are coordinated in a distorted octahedral fashion with facial arrangement of the Pt‐N and Pt‐O bonding to one theophylline ligand and a further Pt‐N bond to a second theophylline ligand. Theophyiline functions thereby as bridging ligand, which is bidentate on one side and monodentate on the other. The six theophylline ligands form a layer between three Me 3 Pt groups.