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In‐Situ Blocking of an Aldehyde Function by Formation of (α‐Triphenylphosphoniumalkoxy)‐titanium or ‐niobium Complexes
Author(s) -
Kauffmann Thomas,
Abel Thomas,
Schreer Martin
Publication year - 1988
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198809441
Subject(s) - heptanal , aldehyde , niobium , in situ , ketone , chemistry , transition metal , blocking (statistics) , titanium , organic chemistry , catalysis , computer science , computer network
Aldehyde functions are selectively blocked in the presence of ketone functions by readily accessible halogeno(phosphane)‐transition‐metal complexes like 1. Thus, the ratio of the methylation products of heptanal and 2‐hexanone could be reversed from ca. 25:1 to 1:9. The formation of complexes like 2 , which is plausible on the basis of the spectroscopic data, is responsible for the blocking.