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Synthesis of Peptides Containing ( S )‐α‐Methylserine
Author(s) -
Altmann Eva,
Altmann KarlHeinz,
Mutter Manfred
Publication year - 1988
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198808581
Subject(s) - side chain , protecting group , chemistry , derivative (finance) , stereochemistry , terminal (telecommunication) , group (periodic table) , amino acid , combinatorial chemistry , biochemistry , computer science , organic chemistry , business , telecommunications , alkyl , polymer , finance
A side‐chain protecting group was not necessary in carrying out the synthesis of a number of dipeptides containing as C‐terminal amino acid the helix‐inducing ( S )‐α‐methylserine. Furthermore, ( S )‐α‐methylserine can be converted into the derivative 1 , bearing a side‐chain protecting group.