Synthesis and Properties of N α ‐Di‐ tert ‐Butoxycarbonyl and N α ‐Benzyloxycarbonyl  tert ‐Butoxycarbonyl Amino Acids | Zendy

Gunnarsson Kerstin | Zendy; Grehn Leif | Zendy; Ragnarsson Ulf | Zendy

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Synthesis and Properties of N α ‐Di‐ tert ‐Butoxycarbonyl and N α ‐Benzyloxycarbonyl tert ‐Butoxycarbonyl Amino Acids

Author(s) -

Gunnarsson Kerstin,

Grehn Leif,

Ragnarsson Ulf

Publication year - 1988

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.198804001

Subject(s) - amino acid , protecting group , chemistry , function (biology) , stereochemistry , group (periodic table) , organic chemistry , biochemistry , biology , alkyl , evolutionary biology

The N ‐protected amino acids 1 and 2 should find universal application ; they are now accessible in good to very good yields. The allyl group has proven to be the best protecting group for the carboxy function. The preparative use of 1 and 2 has been demonstrated by the synthesis of some dipeptides related to Leu‐enkephalin.

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