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A New Route to Nitrile Oxides via α‐Nitrosodiazo Derivatives
Author(s) -
Sicard Ghislaine,
Baceiredo Antoine,
Crocco Guy,
Bertrand Guy
Publication year - 1988
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198803011
Subject(s) - nitrile , carbenoid , group (periodic table) , chemistry , oxide , triple bond , medicinal chemistry , organic chemistry , double bond , catalysis , rhodium
The analogy between a 1,2‐bis(carbenoid) species and a species containing a triple bond, |CNO↔CN→O| , was the basis for the method shown below for the synthesis of nitrile oxides. Noteworthy is the direct introduction of the NO group. Compound 1 is also the first nitrile oxide containing a P‐bound CNO group (R = i Pr 2 N).
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