Premium
Structural Dynamic of Collagen Fibers Cross‐Linked with Isocyanates; Application of Synchrotron Radiation in Macromolecular Chemistry
Author(s) -
Mosler Erika,
Dieringer Hans,
Fietzek Peter P.,
Folkhard Waltraud,
Knörzer Ernst,
Koch Michel H. J.,
Nemetschek Theobald
Publication year - 1987
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198705511
Subject(s) - intermolecular force , fiber diffraction , synchrotron radiation , macromolecule , polymer , synchrotron , chemistry , polymer science , diffraction , polymer chemistry , materials science , chemical physics , x ray crystallography , molecule , organic chemistry , optics , physics , biochemistry
The differentiation between intermolecular and Interfibrillar cross‐linking has been achieved experimentally for collagen fibers for the first time. Decisive for this success was the use of a diisocyanate instead of dialdehydes to carry out the cross‐linking as well as the use of synchrotron radiation. The extent of intermolecular cross‐linking depends on the reaction time. These results should be applicable not only to collagen fibers but also to other fibrous biological polymers and high polymers whose structural dynamics can be studied by X‐ray diffraction analysis.