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The First Direct Evidence for a Cram Chelate
Author(s) -
Reetz Manfred T.,
Hüllmann Michael,
Seitz Thomas
Publication year - 1987
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198704771
Subject(s) - chelation , kinetic energy , chemistry , computational chemistry , inorganic chemistry , physics , quantum mechanics
30 years after their postulation, the existence of Cram chelates has now been demonstrated 13 C‐NMR spectroscopically with the examples 2a/2b . They are formed from 1 and CH 3 TiCl 3 . As shown by labeling experiments and kinetic measurements the methyl transfer 2 → 3 proceeds intermolecularly (not intramolecularly).