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A Simple Access to 2‐Epoxy Alcohols: Titanium( IV )‐Catalyzed Oxygen Transfer from Allylic Hydroperoxides
Author(s) -
Adam Waldemar,
Griesbeck Axel,
Staab Eugen
Publication year - 1986
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198602691
Subject(s) - allylic rearrangement , epoxy , chemistry , catalysis , alcohol , allylic alcohol , titanium , oxygen , combinatorial chemistry , allyl alcohol , organic chemistry , polymer chemistry
A host of new, synthetically valuable 2‐epoxy alcohols 3 should be accessible by the generally applicable title reaction. Oxygen transfer from 1 does not proceed intramolecularly; the first step is the formation of the allylic alcohol 2 , which is epoxidized in a rapid secondary step by 1 to the product 3 . At the same time, compound 2 is reformed.