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Synthetic Equivalent for Aminocarboxycarbene; Synthesis of 1‐Amino‐1‐cyclopropanecarboxylic Acid Methyl Esters
Author(s) -
Schöllkopf Ulrich,
Hauptreif Manfred,
Dippel Joachim,
Nieger Martin,
Egert Ernst
Publication year - 1986
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198601921
Subject(s) - carbene , cyclopropane , ether , chemistry , ethylene , biosynthesis , amino acid , stereochemistry , organic chemistry , ring (chemistry) , biochemistry , catalysis , enzyme
The carbene route to cyclopropane amino acids such as 1a , the parent compound of which is important in the biosynthesis of ethylene, has been employed for the first time. The carbene 4 , which is derived from the bislactim ether of a diketopiperazine, was used as synthetic equivalent for 2 .
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