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A Previously Unrecognized 1 H ‐Azepine Synthesis
Author(s) -
Perst Hartwig,
Massa Werner,
Lumm Michael,
Baum Gerhard
Publication year - 1985
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198508751
Subject(s) - azepine , derivative (finance) , simple (philosophy) , computer science , philosophy , stereochemistry , chemistry , epistemology , business , finance
The 1 H ‐azepine derivative 1 rather than the cyclohexadienylidenamide 3 was the species obtained by Adams and Brower in 1956, as now revealed by an X‐ray analysis. Assignment of the structure on the basis of spectroscopic data was—and still is—not possible in this case. This finding opens up a simple route for the synthesis of other 2‐cyano‐1 H ‐azepines.