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Reactions of Per(chloro, fluoro)ethanes with Aryloxide and Alkoxide Ions — Evidence for Chlorophilic Attack on CCl Bonds
Author(s) -
Li Xingya,
Pan Heqi,
Jiang Xikui,
Zhan Zhengyun
Publication year - 1985
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198508711
Subject(s) - nucleophile , alkoxide , alkyl , chemistry , aryl , medicinal chemistry , ion , organic chemistry , catalysis
The synthesis of aryl‐ and alkyl per(chloro, fluoro) ethyl ethers 2 is achieved by reaction of nucleophiles ROK with the substrates 1 (X, YCl, F). This is the first confirmed example for the attack of oxygen nucleophiles on the CCl bond. The ethers 2 are only obtainable with difficulty by others routes.