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Crinipellins, the First Natural Products with a Tetraquinane Skeleton
Author(s) -
Anke Timm,
Heim Jutta,
Knoch Falk,
Mocek Ursula,
Steffan Bert,
Steglich Wolfgang
Publication year - 1985
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198507091
Subject(s) - derivative (finance) , fungus , ketone , stereochemistry , methylene , chemistry , skeleton (computer programming) , traditional medicine , organic chemistry , biology , botany , medicine , business , finance , anatomy
The range of cyclopentanoid natural products that exhibit antibiotic activity is expanded by the isolation of the crinipellins, for example, crinipellin A 1a and its O‐acetyl derivative 1b . These diterpenoids, which contain an α‐methylene ketone group, are produced by cultures of the fungus Crinipellis stipitaria.