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Isolation of the ( E )‐Enols of β‐Ketocarboxylic Acid Derivatives
Author(s) -
Meier Herbert,
Lauer Wolfgang,
Scholter Friedrich Ulrich
Publication year - 1985
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198503501
Subject(s) - isolation (microbiology) , chemistry , stereochemistry , medicinal chemistry , organic chemistry , bioinformatics , biology
The first examples of ( E )‐enols of β‐dicarbonyl compounds are provided by the isolation of the methyl ester, X = OMe, and the morpholide, X = NC 4 H 8 O. Their melting points as well as their IR and NMR spectra differ clearly from those of the ( Z )‐isomers, which were also isolated.