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An Azacyclophane Derivative as Catalyst of Substrate‐ and Product‐Selective Reactions with Ambident Anions
Author(s) -
Schneider HansJörg,
Busch Rainer
Publication year - 1984
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198409111
Subject(s) - nucleophile , selectivity , chemistry , catalysis , substrate (aquarium) , derivative (finance) , product inhibition , kinetics , saturation (graph theory) , medicinal chemistry , reaction rate , product (mathematics) , combinatorial chemistry , photochemistry , inorganic chemistry , non competitive inhibition , organic chemistry , enzyme , oceanography , physics , mathematics , quantum mechanics , combinatorics , financial economics , economics , geology , geometry
An increase in reaction rate and alteration of the product ratio in nucleophilic exchange reactions is achieved when the azacyclophane 1 described in the two previous communications is added to the reaction of ambident nucleophiles with 2‐bromomethylnaphthalene. Similarly as in the case of enzymes, saturation kinetics and competitive inhibition are observed as well as substrate and product selectivity.