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Transallenation of 1,3‐Bis(dialkylamino)‐1,3‐diethoxyallenes with Disubstituted Malonyl Chlorides
Author(s) -
Saalfrank Rolf W.,
Rost Walter,
Schütz Franz,
Röss Ulrike
Publication year - 1984
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198406371
Subject(s) - chemistry , equivalent , medicinal chemistry , organic chemistry , biochemistry
A general synthetic route to 1,1‐allenedicarboxamides 3 is transallenation . For this purpose 1,3‐bis (dialkylamino) allenes (synthetic equivalents of malonamide dianions 1 ) are allowed to react with disubstituted malonyl chlorides (synthetic equivalents of 1,1‐vinylidene dications 2 ); R 1 NR 2 .