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Ferrocenium Salts—The First Antineoplastic Iron Compounds
Author(s) -
KöpfMaier Petra,
Köpf Hartmut,
Neuse Eberhard W.
Publication year - 1984
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198404561
Subject(s) - metallocene , ferrocene , chemistry , ehrlich ascites , salt (chemistry) , ascites , medicinal chemistry , inorganic chemistry , stereochemistry , organic chemistry , tumor cells , medicine , cancer research , electrochemistry , electrode , polymerization , polymer
The suprising activity of the action of 1 against Ehrlich ascites tumor in mice must be explainable in terms other than that of the activity of the metallocene dihalogenides of d‐electron‐deficient transition‐metals, since the anions in 1 are not coordinated but bound in a salt‐like way. Ferrocene is inactive in the same test.