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Synthesis of 1,2 :3,4 :5,6‐Trianhydrohexitols with gluco ‐, manno ‐, and ido ‐Configuration
Author(s) -
Köll Peter,
Oelting Michael,
Kopf Jürgen
Publication year - 1984
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198402421
Subject(s) - diastereomer , stereochemistry , chemistry , hexane , philosophy , organic chemistry
The first hexane triepoxides have been synthesized from the corresponding trans ‐3,4‐unsaturated diepoxides. Thus, the D ‐ erythro educt afforded the diastereomers with the D ‐ manno ‐ and D ‐ ido ‐configuration (see figure).—Analogous diepoxides exhibit both carcinogenic and tumorstatic activity.
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