Oxidative Cleavage of Pyrocatechol at the  meta ‐Position; A Model Reaction for Cleavage by Pyrocatechol‐2,3‐dioxygenase? | Zendy

Müller Rudolf | Zendy; Lingens Franz | Zendy

Premium

Oxidative Cleavage of Pyrocatechol at the meta ‐Position; A Model Reaction for Cleavage by Pyrocatechol‐2,3‐dioxygenase?

Author(s) -

Müller Rudolf,

Lingens Franz

Publication year - 1984

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.198400791

Subject(s) - oxidative cleavage , chemistry , cleavage (geology) , picolinic acid , sulfoxide , dioxygenase , oxidative phosphorylation , dimethyl sulfoxide , medicinal chemistry , stereochemistry , organic chemistry , catalysis , biochemistry , enzyme , materials science , fracture (geology) , composite material

The first nonenzymatic meta ‐cleavage of pyrocatechol 1 was achieved with KO 2 in dimethyl sulfoxide. The unstable yellow 2‐hydroxymuconaldehyde acid 2 was converted into picolinic acid. Since 1 is not cleaved to give 2 under N 2 , O 2 ⊖as well as O 2 might participate in the reaction.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research