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18,19‐Didehydrocorrinoids—Possible Intermediates in the Biosynthesis of Vitamin B 12
Author(s) -
Dresow Bernd,
Ernst Ludger,
Grotjahn Lutz,
Koppenhagen Volker B.
Publication year - 1981
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198110481
Subject(s) - cobalt , biosynthesis , chemistry , vitamin b , stereochemistry , metal , vitamin , biochemistry , organic chemistry , enzyme
A common biosynthetic precursor of metal‐free and cobalt‐containing corrinoids could be the 18,19‐didehydrocobyrinic acid c ‐am‐de (1) in its cobalt‐free form; the structure of (1) was determined, in particular, by 1 H‐and 13 C‐NMR spectroscopic investigation of its hexamethyl ester.