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Synthesis of [10‐ 13 C]Secologanin
Author(s) -
Tietze LutzF.,
Henke Stephan
Publication year - 1981
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198109701
Subject(s) - biogenesis , chemistry , wittig reaction , stereochemistry , identification (biology) , biology , botany , biochemistry , gene
Secologanin ( 1 ) plays a key role in the biogenesis of a series of alkaloids. Compound ( 1 ) labeled with 13 C at position 10, which should enable identification of non‐isolated intermediates, can be prepared from unlabeled ( 1 ), inter alia, via OsO 4 − and Pb(OAc) 4 ‐oxidation and a Wittig olefination.