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The 2‐Chlorooxirane–α‐Chloroketone Reactivity Spectrum
Author(s) -
Gasteiger Johann,
Herzig Christian
Publication year - 1981
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198108681
Subject(s) - phosphonate , reactivity (psychology) , nucleophile , phosphate , chemistry , spectrum (functional analysis) , broad spectrum , medicinal chemistry , organic chemistry , combinatorial chemistry , physics , catalysis , medicine , pathology , alternative medicine , quantum mechanics
2‐Chlorooxiranes (3) are not only more reactive than 2‐chloroketones (1) , but also react with nucleophiles to give other products. Thus, (1) reacts with P(OMe) 3 to give the phosphate (2) , while (3) yields the phosphonate (4) .
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