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Macrotricyclic Quaternary Ammonium Salts: Enzyme‐Analogous Activity
Author(s) -
Schmidtchen Franz P.
Publication year - 1981
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198104662
Subject(s) - ammonium , methyl iodide , chemistry , quaternary , iodide , enzyme , decomposition , diastereomer , protein quaternary structure , enzyme assay , medicinal chemistry , organic chemistry , biochemistry , biology , protein subunit , paleontology , gene
Reactions in presence of the low molecular weight, modifiable enzyme models (1) and (2) lead in some cases to surprising results. Thus, (1) inhibits the reaction of fluorodini‐trobenzene with N 3 ⊖ , whereas (2) accelerates this reaction, as well as that of methyl iodide with N 3 ⊖and the decomposition of erythro ‐ (3) .