Reductive Cleavage of 3‐Oxazolin‐5‐ones; Application to the Synthesis of β,γ‐Unsaturated Ketones from Allyl,  N ‐Acyl‐2‐phenylglycinates | Zendy

Niewöhner Ulrich | Zendy; Steglich Wolfgang | Zendy

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Reductive Cleavage of 3‐Oxazolin‐5‐ones; Application to the Synthesis of β,γ‐Unsaturated Ketones from Allyl, N ‐Acyl‐2‐phenylglycinates

Author(s) -

Niewöhner Ulrich,

Steglich Wolfgang

Publication year - 1981

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.198103951

Subject(s) - chemistry , reagent , squalene , formamide , cleavage (geology) , aqueous solution , medicinal chemistry , chromium , organic chemistry , materials science , fracture (geology) , composite material

β, γ‐Unsaturated ketones (3) , including those with squalene framework, have been synthesized in good yields from 3‐oxazolinones (2) . The most suitable reagent was found to be chromium( II ) acetate with aqueous H 3 PO 2 in dimethyl‐formamide. The oxazolinones are obtained from the allyl esters (1) .

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