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Preparation of Labeled Aldehydes and Ketones from Enamides
Author(s) -
Golding Bernard T.,
Wong Ah Kee
Publication year - 1981
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198100891
Subject(s) - chemistry , nuclear magnetic resonance spectroscopy , combinatorial chemistry , simple (philosophy) , ketone , organic chemistry , philosophy , epistemology
The optimal use of 17 O‐NMR spectroscopy requires simple methods for 17 O‐labeling. The favorable rearrangement of the carbonyl compounds (1) via imines (2) and enamides (3) into labeled carbonyl compounds (1 *) is outlined below.