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Intramolecular Oxidative Cyclization of 3‐Benzyl‐1,2,3,4‐tetrahydroisoquinolines
Author(s) -
Hartenstein Johannes,
Heigl Theo,
Satzinger Gerhard
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198010181
Subject(s) - intramolecular force , chemistry , oxidative phosphorylation , stereochemistry , biochemistry
Nature seemed to have overlooked 3‐benzyl‐1,2,3,4‐tetrahydroisoquinolines , which is surprising in view of the enormous importance of 1‐benzyl isomers. Model reactions on tetraalkoxy derivatives have now afforded the polycyclics (1) resembling natural morphinadienones.