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UV Irradiation of Nucleic Acids and Their Components in the Presence of Air
Author(s) -
Fahr Egon,
Fecher Peter,
Roth Georg,
Wüstenfeld Peter
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198008291
Subject(s) - uracil , thymine , cytosine , nucleic acid , pyrimidine , irradiation , chemistry , aqueous solution , in vivo , radiochemistry , photochemistry , biochemistry , organic chemistry , dna , biology , genetics , physics , nuclear physics
Pyrimidine bases can give different products on UV irradiation in the presence and the absence of air; hence the action of UV radiation in vivo cannot be deduced solely from in vitro experiments conducted with exclusion of air. A remarkable observation made on UV irradiation of cytosine, uracil, thymine, and similar bases in aqueous solution in the presence of air is the elimination of CO. Perhaps CO is formed in nature by such reactions.