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Absolute Configuration of the Cancerostatic S (–)‐Isophosphamide
Author(s) -
Adamiak Dorota A.,
Gdaniec Maira,
Pankiewicz Krzysztof,
Stec Wojciech J.
Publication year - 1980
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.198005491
Subject(s) - absolute configuration , absolute (philosophy) , stereochemistry , chemistry , philosophy , theology
Structure/activity relations in chiral drugs can only be studied if the absolute configuration is known. The levorotatory form of the cancerostatic isophos‐phamide is shown by X‐ray structure analysis to have the S configuration.